SHAFAQNA TURKEY. A team of scientists from McMaster University and the Massachusetts Institute of Technology have discovered a new antibiotic that can be used to kill a deadly supervirus, according to a new study published in the journal Nature Chemical Biology.
We are talking about the supermicrobe Acinetobacter baumannii, which the World Health Organization has classified as a “critical” threat among its “predecessor pathogens”.
This pathogen is a family of bacteria that pose the “biggest threat” to human health.
According to the World Health Organization, bacteria have a built-in ability to find new ways to resist treatment and are able to pass on genetic material that allows other bacteria to become resistant to drugs.
Baumannium poses a threat to hospitals, nursing homes and patients requiring a ventilator and blood catheter, as well as patients with open wounds after surgery.
Bacteria can live for long periods in environmental services and shared equipment, and can often be spread by hand.
Baumannii can cause urinary tract and lung infections in addition to blood infections.
According to the Centers for Disease Control and Prevention, bacteria can “colonize” or live in a patient’s body without causing infection or symptoms.
Thursday’s study showed that researchers used an artificial intelligence algorithm to test thousands of antibacterial molecules in an attempt to predict new structural classes.
As a result of the AI scan, the researchers were able to identify a new antibacterial compound, which they named abaucin.
“We had a lot of data telling us which chemicals could and could not kill a group of bacteria,” said Gary Liu, a McMaster University graduate student. “My job was to train this model, and all this model had to do was tell us if the new molecules would have antibacterial properties,” he said.
After the scientists trained the AI model, they used it to analyze 6,680 compounds they had never encountered before.
The analysis took an hour and a half, after which several hundred compounds were obtained, 240 of which were tested in the laboratory.
Laboratory tests eventually identified nine potential antibiotics, including abaucin.
TRT
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